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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360955Generated: October 31, 2026

Aniline → 4-Nitrodiphenylamine

https://huagongshe.com/reaction/2360955

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
Reactant1-Chloro-4-nitrobenzeneHCID 7474—
ReactantFormanilideHCID 7671—
ReactantPotassium CarbonateHCID 11430—
SolventFormic AcidHCID 284—
Product4-NitrodiphenylamineHCID 13271—

Reaction Steps

formanilide method, where formic acid and aniline are used as starting materials to prepare formanilide, which in turn reacts with p-nitro-chlorobenzene in the presence of an acid-binding agent such as potassium carbonate, to produce 4-nitrodiphenylamine, and then, 4-nitrodiphenylamine is reduced by sodium sulfide to form 4-aminodiphenylamine;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686188B2
Source datasetuspto-grants-2014_04
ORD IDord-454803d8aaad46a6aeb01563dd42b4fe
Source noteuspto-grants-2014_04