HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 4-[(4-Chlorophenyl)sulfanyl]piperidine--hydrogen chloride (1/1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Phenyl chloroformate | HCID 15891 | — |
| Reactant | HCID 13607968 | HCID 13607968 | — |
| Product | 4-[(4-Chlorophenyl)sulfanyl]piperidine--hydrogen chloride (1/1) | HCID 17749800 | — |
Reaction Steps
Following the procedure of Intermediate 9, 4-[(4-chlorophenyl)thio]-1-(phenylmethyl)piperidine is reacted with phenyl chloroformate and the product is hydrolyzed with 48% hydrobromic acid to give the free base of the title compound which is then converted to the hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04642348 |
| Source dataset | uspto-grants-1987_02 |
| ORD ID | ord-d1a48958fbb34e93950a9e9ec568d8c8 |
| Source note | uspto-grants-1987_02 |