HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroquinoline → HCID 46931464, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroquinoline | HCID 11928 | — |
| Reactant | 2-Cyanopyridine-5-boronic acid pinacol ester | HCID 16414188 | — |
| Product | HCID 46931464 | HCID 46931464 | 3% |
Reaction Steps
A from 2-chloroquinoline (82 mg, 0.5 mmol) and 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile (115 mg, 0.5 mmol). The product was obtained as yellow solid (3 mg, 3%). 1H NMR (400 MHz, CDCl3): δ 9.48 (dd, J=2.4, 0.8 Hz, 1H), 8.69 (dd, J=8.0, 2.0 Hz, 1H), 8.33 (d, J=8.8 Hz, 1H), 8.19 (d, J=8.4 Hz, 1H), 7.93 (d, J=8.4 Hz, 1H), 7.90 (dd, J=8.4, 1.2 Hz, 1H), 7.87 (dd, J=8.4, 0.8 Hz, 1H), 7.81 (m, 1H), 7.63 (m, 1H); MS (ESI):232 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691187B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-eadb184dba674456abde89875fa14bf6 |
| Source note | uspto-grants-2014_04 |