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HRID2361491

反应详情

EQUATION

反应方程式

HRID 2361491 的结构方程式

REACTANTS

反应物

2
结构：O=[N+]([O-])c1cc(Br)nc2ccccc12
HCID581266

2-Bromo-4-nitroquinoline

C9H5BrN2O2

结构：CN(C)c1ccc(B(O)O)cn1
HCID2763271

6-(Dimethylamino)pyridine-3-boronic acid

C7H11BN2O2

PRODUCTS

生成物

1
结构：CN(C)c1ccc(-c2cc([N+](=O)[O-])c3ccccc3n2)cn1
HCID58362513

未命名化合物

PROCEDURE

实验过程

N,N-Dimethyl-5-(4-nitroquinolin-2-yl)pyridin-2-amine T480P was prepared using general procedure A from 2-Bromo-4-nitroquinoline (50 mg, 0.2 mmol) and (6-(dimethylamino)pyridin-3-yl)boronic acid (34 mg, 0.2 mmol). The product was obtained as a yellow solid (40 mg, 68%). 1H NMR (400 MHz, CDCl3): δ 8.99 (d, J=2.4 Hz, 1H), 8.36-8.34 (m, 2H), 8.30 (s, 1H), 8.19 (m, 1H), 7.81 (m, 1H), 7.65 (m, 1H), 6.66 (d, J=9.0 Hz, 1H), 3.21 (s, 6H); MS (ESI): 295 (M+H+).