1-Chloro-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile → HCID 58362619, compound

Participants

Reaction Steps

General experimental procedure (A) for Suzuki coupling reaction with 4-aminophenyl boronic acid was followed. Reaction was performed on a 241 mg scale of 1-chloro-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile. Isolated 100 mg (34%) of T672 as a yellow solid. NMR (CD3OD): δ 7.85 (1H, d, J=8.4 Hz), 7.66 (1H, m), 7.43 (2H, m), 7.26-7.30 (2H, m, overlapped), 7.07 (1H, d, J=8.4 Hz), 7.38 (1H, dd, J=9.0, 2.6 Hz), 6.97 (2H, m), 2.80 (3H, s); MS: 299 (M+H+).

Provenance & Evidence