HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,7,8-Tetramethyl-1,10-phenanthroline → HCID 44477079, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,7,8-Tetramethyl-1,10-phenanthroline | HCID 74265 | — |
| Reactant | 1-Iodo-4-(trifluoromethoxy)benzene | HCID 2777294 | — |
| Reactant | HCID 44462713 | HCID 44462713 | — |
| Product | HCID 44477079 | HCID 44477079 | — |
Reaction Steps
In a similar fashion (Route 21, GP J) except for replacing phenanthroline with 3,4,7,8-tetramethylphenanthroline, 1-[(4-cyclobutyl-1,4-diazepan-1-yl)carbonyl]azetidin-3-ol (50 mg, 0.19 mmol) and 1-iodo-4-(trifluoromethoxy)benzene (86 mg, 0.3 mmol) gave the title compound as colourless oil after purification by preparative HPLC (44 mg, 52%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691804B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-4e0f63e1b6674110a554de1b56a39fe3 |
| Source note | uspto-grants-2014_04 |