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HRID2361657

反应详情

EQUATION

反应方程式

HRID 2361657 的结构方程式

REACTANTS

反应物

3
结构：Cc1cnc2c(ccc3c(C)c(C)cnc32)c1C
HCID74265

1,10-Phenanthroline, 3,4,7,8-tetramethyl-

C16H16N2

结构：FC(F)Oc1ccc(I)cc1
HCID2737008

1-(difluoromethoxy)-4-iodobenzene

C7H5F2IO

结构：O=C(N1CCCN(C2CCC2)CC1)N1CC(O)C1
HCID44462713

未命名化合物

PRODUCTS

生成物

1
结构：O=C(N1CCCN(C2CCC2)CC1)N1CC(Oc2ccc(OC(F)F)cc2)C1
HCID44477080

未命名化合物

PROCEDURE

实验过程

In a similar fashion (Route 21, GP J) except for replacing phenanthroline with 3,4,7,8-tetramethylphenanthroline, 1-[(4-cyclobutyl-1,4-diazepan-1-yl)carbonyl]azetidin-3-ol (50 mg, 0.19 mmol) and 1-(difluoromethoxy)-4-iodobenzene (81 mg, 0.3 mmol) gave the title compound as colourless oil after purification by preparative HPLC (47 mg, 57%).