HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,7,8-Tetramethyl-1,10-phenanthroline → HCID 44477081, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,7,8-Tetramethyl-1,10-phenanthroline | HCID 74265 | — |
| Reactant | 4-Chloro-2-fluoro-1-iodobenzene | HCID 2736562 | — |
| Reactant | HCID 44462713 | HCID 44462713 | — |
| Product | HCID 44477081 | HCID 44477081 | — |
Reaction Steps
In a similar fashion (Route 21, GP J) except for replacing phenantroline with 3,4,7,8-tetramethylphenantroline, 1-[(4-cyclobutyl-1,4-diazepan-1-yl)carbonyl]azetidin-3-ol (50 mg, 0.19 mmol) and 4-chloro-2-fluoro-1-iodobenzene (77 mg, 0.3 mmol) gave the title compound as colourless oil after purification by preparative HPLC (60 mg, 61%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691804B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-930b1cfad2db49bfa74d97fd808a920d |
| Source note | uspto-grants-2014_04 |