HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,7,8-Tetramethyl-1,10-phenanthroline → HCID 44477163, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,7,8-Tetramethyl-1,10-phenanthroline | HCID 74265 | — |
| Reactant | 5-Bromo-2-(trifluoromethyl)pyridine | HCID 2761197 | — |
| Reactant | HCID 44462713 | HCID 44462713 | — |
| Product | HCID 44477163 | HCID 44477163 | — |
Reaction Steps
In a similar fashion (Route 21, GP J) except for replacing phenantroline with 3,4,7,8-tetramethylphenantroline, 1-[(4-cyclobutyl-1,4-diazepan-1-yl)carbonyl]azetidin-3-ol (50 mg, 0.20 mmol) and 5-bromo-2-trifluoromethylpyridine (59 mg, 0.26 mmol) gave the title compound as a brown oil after purification by preparative HPLC (15 mg, 14%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691804B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-180a111bdf40471a85e29283203d1ac9 |
| Source note | uspto-grants-2014_04 |