HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → HCID 58243419, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | HCID 58243368 | HCID 58243368 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 58243419 | HCID 58243419 | 14.2% |
Reaction Steps
In a similar fashion (Route 1, GP A; except that MeCN was used as solvent), 5-{[1-(1,4-diazepan-1-ylcarbonyl)azetidin-3-yl]oxy}-N-methylpyridine-2-carboxamide (25 mg, 0.075 mmol) and acetone (5.5 μl, 0.075 mmol) gave the title compound as colourless oil (4 mg, 14%) after purification by preparative HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691804B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-626d0d0d019f4967b35f0fd2f98c3905 |
| Source note | uspto-grants-2014_04 |