Tributylstannane → HCID 71007967, compound

Participants

Reaction Conditions

Reaction Steps

The mixture of iodide 5A (0.18 mmol), AIBN (0.054 mmol), and Bu3SnH (0.54 mmol) was diluted with toluene (10 mL) and the reaction mixture was heated at 90° C. for 2 h. The reaction mixture was concentrated and the residue was purified by silica gel chromatography (10/90 EtOAc/Hexane) to provide the reduction product 6A in 73% yield. Data: LC/MS (ESR) m/z 266 [M+1]+.

Provenance & Evidence