2-Aminophenol → HCID 66726405, compound

Participants

Reaction Steps

A mixture of 2-aminophenol (1 g, 9.164 mmol), tetrahydropyran-4-one (1.099 ml, 11.913 mmol), and sodium triacetoxyborohydride (0.71 g, 3.42 mmol) in DCE (50 ml) was stirred at room temperature for 16 h. The crude mixture was filtered over diatomaceous earth, washed with DCM and the filtrate was evaporated in vacuo to yield D2O (0.69 g) which was used as such in the next reaction step without further purification.

Provenance & Evidence