HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl isocyanate → HCID 67448806, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl isocyanate | HCID 76639 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Ethyl 1-(aminomethyl)cyclopropanecarboxylate | HCID 11480505 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 67448806 | HCID 67448806 | 106% |
Reaction Steps
According to the procedure described in the synthesis method of Compound V-1 with the modification that the reaction solvent was changed to CH2Cl2 and DIPEA (1.6 ml, 9.3 mmol) was added, ethyl 1-(aminomethyl)cyclopropanecarboxylate (880 mg, 6.2 mmol) was reacted with benzyl isocyanate (1.15 ml, 8.0 mmol) to obtain the title compound (1.64 g, 106%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691819B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-78f6b01905d34dba816588283364d63f |
| Source note | uspto-grants-2014_04 |