(S)-N-Cbz-1,1-diethoxypropan-2-amine → (2S)-1,1-Diethoxy-2-propanamine

To a solution of (S)-benzyl 1,1-diethoxypropan-2-ylcarbamate (844 mg, 3.00 mmol) in methanol (50 ml) was added 5% palladium on carbon (30 mg) and the mixture was stirred at room temperature for 2 hr under hydrogen atmosphere. The reaction mixture was filtered on Celite and washed with methanol (200 ml) and the filtrate was concentrated in vacuo to obtain the title compound (442 mg, 100%).

1. filtrationThe reaction mixture was filtered on Celite
2. washwashed with methanol (200 ml)
3. concentrationthe filtrate was concentrated in vacuo

ORD record

ord-f099a669951f4b8aa112bc978974144a

Source dataset

uspto-grants-2014_04

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US08691819B2