HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Quinolinecarboxaldehyde → (S)-1,1-diethoxy-N-(quinolin-8-ylmethyl)propan-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Quinolinecarboxaldehyde | HCID 170103 | — |
| Reactant | (2S)-1,1-Diethoxy-2-propanamine | HCID 12398111 | — |
| Product | (S)-1,1-diethoxy-N-(quinolin-8-ylmethyl)propan-2-amine | HCID 67074994 | 90.7% |
Reaction Steps
According to the procedure described in the synthesis is method of Compound IX-6, (S)-1,1-diethoxypropan-2-amine (Compound XVIII-1) (442 mg, 3.00 mmol) was reacted with 8-quinolinecarboaldehyde (393 mg, 2.50 mmol) to obtain the title compound (649 mg, 90.7%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691819B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-86f3efdca0e54ec696b10c8bf8ab29ea |
| Source note | uspto-grants-2014_04 |