Phenethyl bromide → N-(2-Phenylethyl)aminoacetaldehyde diethyl acetal

Participants

Reaction Steps

According to the procedure described in the synthesis method of Compound IX-1, 2,2-diethoxyethanamine (5.82 ml, 40 mmol) was reacted with (2-bromoethyl)benzene (2.70 ml, 20 mmol) and the obtained residue was purified by Büch silica gel column chromatography (chloroform only) to obtain the title compound (4.45 g, 94%).

Provenance & Evidence