Dimethylamine → 2-[2-(Dimethylamino)ethyl]-2,3-dihydro-4-methyl-1,4-oxazepino[6,7-h]quinoline-5(4H)-thione hydrochloride

HRID 236201Notes

Reaction equation

HRID 236201 reaction equation
[Cl:1][CH2:2][CH2:3][CH:4]1[CH2:18][N:17]([CH3:19])[C:16](=[S:20])[C:7]2[CH:8]=[CH:9][C:10]3[CH:11]=[CH:12][CH:13]=[N:14][C:15]=3[C:6]=2[O:5]1.[CH3:21][NH:22][CH3:23]>>[ClH:1].[CH3:21][N:22]([CH3:23])[CH2:2][CH2:3][CH:4]1[CH2:18][N:17]([CH3:19])[C:16](=[S:20])[C:7]2[CH:8]=[CH:9][C:10]3[CH:11]=[CH:12][CH:13]=[N:14][C:15]=3[C:6]=2[O:5]1

Participants

3

Reactant 2

HCID 674DimethylamineHCID 212715722-(2-chloroethyl)-2,3-dihydro-4-methyl-1,4-oxazepino[6,7-h]quinoline-5(4H)-thione

Product 1

HCID 212715642-[2-(Dimethylamino)ethyl]-2,3-dihydro-4-methyl-1,4-oxazepino[6,7-h]quinoline-5(4H)-thione hydrochloride

Procedure

Following the procedure of Example 31, 2-(2-chloroethyl)-2,3-dihydro-4-methyl-1,4-oxazepino[6,7-h]quinoline-5(4H)-thione is reacted with dimethylamine to give the title compound.

Sources & evidence

ORD record
ord-cff4ea8645454cfebed44c7f72c2b664
Source dataset
uspto-grants-1987_02
Patent number
US04642343

Reaction notes

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