HCID 66823376, compound → HCID 66823461, compound

HRID 2362177Notes

Reaction equation

HRID 2362177 reaction equation
[C:1]([O:5][C:6](=[O:33])[NH:7][C:8]1([C:14]2[CH:19]=[CH:18][C:17]([C:20](=O)[C:21]([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)=[CH:22]N(C)C)=[CH:16][CH:15]=2)[CH2:11][C:10]([OH:13])([CH3:12])[CH2:9]1)([CH3:4])([CH3:3])[CH3:2].[C:34]1([C:40]2[NH:41][C:42]([NH2:45])=[N:43][N:44]=2)[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1>C(O)(=O)C.C(O)C>[C:1]([O:5][C:6](=[O:33])[NH:7][C:8]1([C:14]2[CH:15]=[CH:16][C:17]([C:20]3[C:21]([C:26]4[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=4)=[CH:22][N:43]4[N:44]=[C:40]([C:34]5[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=5)[N:41]=[C:42]4[N:45]=3)=[CH:18][CH:19]=2)[CH2:9][C:10]([OH:13])([CH3:12])[CH2:11]1)([CH3:2])([CH3:3])[CH3:4]

Participants

5

Reactant 2

HCID 66823376HCID 66823376, compoundHCID 178509136HCID 178509136, compound

Product 1

HCID 66823461HCID 66823461, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 702EthanolSolvent

Procedure

A mixture of 2 (270 mg, 0.6 mmol) and 5-Phenyl-4H-[1,2,4]triazol-3-ylamine (96 mg, 0.6 mmol) in acetic acid (1 mL) and ethanol (4 mL) was heated under reflux for 6 hours.

Workup

  1. temperaturewas heated
  2. temperatureunder reflux for 6 hours

Sources & evidence

ORD record
ord-e4684533dd084b5a9ad3a895025e0c38
Source dataset
uspto-grants-2014_04
Patent number
US08691825B2

Reaction notes

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