HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 66719183, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 66719127 | HCID 66719127 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 66719183 | HCID 66719183 | 92.6% |
Reaction Steps
To the solution of 8-5 (50 mg, 0.1 mmol) in 1 mL of DCM was added TFA (1 mL) and the mixture was stirred at room temperature for 3 h. The mixture was concentrated by evaporation and the residue was purified by prep.HPLC to give the product 8-6 (37 mg, yield 92.5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691825B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-5d1a9176e9bb4469b8a8b4ce2c1e17f2 |
| Source note | uspto-grants-2014_04 |