Phosgene → 2-Chloro-6-phenylbenzenesulfonyl Isocyanate

Participants

Reaction Steps

A mixture of 9.5 g (0.026 mol) of N-(butylaminocarbonyl)-2-chloro-6-phenylbenzenesulfonamide of Example 3 and 0.02 g DABCO was heated in 120 ml dry xylenes to reflux (138°) with a short water condenser and dry ice cold finger condenser attached. An excess of phosgene gas was introduced and reflux was continued for 2 hours. The mixture was then cooled, filtered under nitrogen atmosphere then evaporated to an amber oil, 8.5 g. An infrared spectrum exhibited an absorption at 2250 cm-1 indicating the title compound.

Provenance & Evidence