4-Chloro-6-methylpyrimidine → HCID 86673425, compound

HRID 2362387Notes

Reaction equation

HRID 2362387 reaction equation
Br[C:2]1[N:7]=[C:6]([CH2:8][Br:9])[CH:5]=[CH:4][N:3]=1.[Cl:10]C1C=C(C)N=CN=1>>[Br:9][CH2:8][C:6]1[CH:5]=[C:4]([Cl:10])[N:3]=[CH:2][N:7]=1

Participants

3

Reactant 2

HCID 5817964-Chloro-6-methylpyrimidineHCID 86673424HCID 86673424, compound

Product 1

HCID 86673425HCID 86673425, compound

Procedure

Prepared according to the same procedure as 2-bromo-4-(bromomethyl)pyrimidine, starting with 4-chloro-6-methylpyrimidine. 1H NMR (500 MHz, DMSO-d6) δ 9.07 (s, 1H), 7.91 (d, J=0.9 Hz, 1H), 4.66 (s, 2H), Mass spec.: 208.9 (MH)+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b91dd782d1aa4cd6bdd1210d2a663c80
Source dataset
uspto-grants-2014_04
Patent number
US08691821B2

Reaction notes

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