Rac-1-(2-furyl)-2-(methylamino)ethanol → 4-(2-amino-2-oxoethyl)-N-(4-chlorobenzyl)-2-{[[2-(2-furyl)-2-hydroxyethyl](methyl)amino]methyl}-3-methyl-7-oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamide

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Reaction Steps

Prepared from 1-(2-furyl)-2-(methylamino)ethanol (Preparation 8) and 4-(2-amino-2-oxoethyl)-N-(4-chlorobenzyl)-2-(chloromethyl)-3-methyl-7-oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamide by the procedure described for Example 2. Recrystallization from acetonitrile afforded 17 mg of the title compound as a white solid.

Provenance & Evidence