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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2362608Generated: October 29, 2026

8-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine → HCID 67250622, compound

https://huagongshe.com/reaction/2362608

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amineHCID 12741417—
Reactant(Pyrazolo[1,5-a]pyridin-3-yl)acetic acidHCID 14145809—
ProductHCID 67250622HCID 67250622—

Reaction Steps

Synthesis works according to the preparation of A4-1 or A4-4 when using N-(8-methoxytetralin-2-yl)-N-propylamine (A2-1: R=OMe) and 3-pyrazolo[1,5-a]pyridinyl acetic acid (A3-13: R=OMe, Cy=3-pyrazolo[1,5-a]pyridinyl) (synthesis according to literature: Gmeiner, P. Arch Pharm 1988, Vol 321, p 517) and subsequent reaction according to the synthesis of A5-1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08691839B2
Source datasetuspto-grants-2014_04
ORD IDord-8b5d7eea8ebf4d51bdfa9b89b424b50a
Source noteuspto-grants-2014_04