HCID 67003668, compound → HCID 54673098, compound

Participants

Reaction Steps

The title compound was prepared as described in Example 22E, substituting 1-(5-(5-chloro-2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl)thiazol-2-yl)cyclobutanol (Example 75B) for 1 tert-butyl 3-(3-(5-chloro-4-(2-(1-(methoxymethoxy)cyclobutyl)thiazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl)-1,2,4-oxadiazol-5-yl)piperidine-1-carboxylate (Example 22D). 1H NMR (500 MHz, DMSO-d6) ppm 12.42 (s, 1H) 8.29 (s, 1H) 8.25 (s, 1H) 7.56 (d, 1H) 7.49 (dd, 1H) 6.94 (m, 2H) 6.66 (s, 1H) 4.29 (s, 4H) 2.63 (m, 2H) 2.41 (m, 2H) 1.97 (m, 2H); MS ESI(+) m/z 440.0 [M+H]+.

Provenance & Evidence