4-Bromo-1-(cyclopropylmethyl)pyridin-2(1H)-one → 4-bromo-1-butylpyridin-2(1H)-one

HRID 2362806Notes

Reaction equation

HRID 2362806 reaction equation
C(N1C=CC(O)=CC1=O)CCC.[Br:13][C:14]1[CH:19]=[CH:18][N:17]([CH2:20][CH:21]2[CH2:23][CH2:22]2)[C:16](=[O:24])[CH:15]=1>>[Br:13][C:14]1[CH:19]=[CH:18][N:17]([CH2:20][CH2:21][CH2:22][CH3:23])[C:16](=[O:24])[CH:15]=1

Participants

3

Reactant 2

HCID 585545154-Bromo-1-(cyclopropylmethyl)pyridin-2(1H)-oneHCID 594970761-butyl-4-hydroxy-1H-pyridine-2-one

Product 1

HCID 594970924-bromo-1-butylpyridin-2(1H)-one

Procedure

Intermediate D7 was prepared from intermediate D5 following the same procedure implemented for the synthesis of D3.

Sources & evidence

ORD record
ord-1bcfac5c14de4bf98b0e7fcbf7244555
Source dataset
uspto-grants-2014_04
Patent number
US08691849B2

Reaction notes

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