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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2362870Generated: October 31, 2026

Hydrochloric Acid → HCID 66652304, compound

https://huagongshe.com/reaction/2362870

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58046786HCID 58046786—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66652304HCID 66652304—

Reaction Steps

To tert-butyl 3-(2-(methoxycarbonyl)benzyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.12 g, 0.25 mmol) was added 4M solution of HCl in dioxane (2.5 mL). After stirring at room temperature for 90 minutes, the reaction mixture was concentrated in vacuo to obtain methyl 2-((4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)methyl)benzoate as a hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08691836B2
Source datasetuspto-grants-2014_04
ORD IDord-3e146af3b1f040399f99871d6ea8956e
Source noteuspto-grants-2014_04