Hydrochloric Acid → Benzyl 6-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)hexanoate

Participants

Reaction Steps

To tert-butyl 3-(6-(benzyloxy)-6-oxohexyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.08 g, 0.15 mmol) was added 4M solution of HCl in dioxane (1.5 mL). After stirring at room temperature for 2 hours, the reaction mixture was concentrated in vacuo to obtain benzyl 6-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)hexanoate as a hydrochloride salt.

Provenance & Evidence