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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2362889Generated: October 30, 2026

Hydrochloric Acid → HCID 66652151, compound

https://huagongshe.com/reaction/2362889

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58046605HCID 58046605—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66652151HCID 66652151—

Reaction Steps

To tert-Butyl 4-oxo-3-(3-((2-oxo-2-(piperidin-1-yl)ethoxy)carbonyl)benzyl)-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.17 g, 0.29 mmol) was added 4M solution of HCl in dioxane (3 mL). After stirring at room temperature for 2 hours, the reaction mixture was concentrated in vacuo to obtain 2-oxo-2-(piperidin-1-yl)ethyl 3-((4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)methyl)benzoate as a hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08691836B2
Source datasetuspto-grants-2014_04
ORD IDord-4d1005b252be46f8b9c2d878ae3b4473
Source noteuspto-grants-2014_04