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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2362912Generated: October 30, 2026

Hydrochloric Acid → HCID 66652155, compound

https://huagongshe.com/reaction/2362912

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58046676HCID 58046676—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66652155HCID 66652155—

Reaction Steps

To tert-butyl 1-(4-fluorophenyl)-3-(3-(methoxycarbonyl)benzyl)-4-oxo-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.42 g, 0.84 mmol) was added 4M solution of HCl in dioxane (5 mL). After stirring at room temperature for 2 hours, the reaction mixture was concentrated in vacuo to obtain methyl 3-((1-(4-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-3-yl)methyl)benzoate as a hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08691836B2
Source datasetuspto-grants-2014_04
ORD IDord-25e561749efe4c2cad96875b2658b580
Source noteuspto-grants-2014_04