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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2363073Generated: October 30, 2026

Hydrochloric Acid → HCID 66652365, compound

https://huagongshe.com/reaction/2363073

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 66652102HCID 66652102—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66652365HCID 66652365—

Reaction Steps

To tert-butyl 3-(4-(methylsulfonamido)phenyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.91 g, 1.82 mmol) was added 4M solution of HCl in dioxane (10 mL). After stirring at room temperature for 18 hours, the reaction mixture was concentrated in vacuo to obtain N-(4-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)phenyl)methanesulfonamide as a hydrochloride salt (0.7 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08691836B2
Source datasetuspto-grants-2014_04
ORD IDord-989c8ea2bb104a34829b7f489246282d
Source noteuspto-grants-2014_04