HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)phenol → HCID 67238766, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)phenol | HCID 7376 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 67111192 | HCID 67111192 | — |
| Product | HCID 67238766 | HCID 67238766 | 51.7% |
Reaction Steps
2-Chloro-thiazole-4-carboxylic acid 3,5-difluoro-4-methanesulfonylamino-benzylamide (62 mg, 0.16 mmol), anhyd. K2CO3 (49 mg, 0.20 mmol) was reacted with 3-trifluoromethylphenol (40 μl, 0.19 mmol) as described above to give the title compound (42 mg, 51%) after purification by column chromatography (Hex/EtOAc=3:2)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691855B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-fbf8e7bb8de74089ac3b67350c86bb1f |
| Source note | uspto-grants-2014_04 |