HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylidene-2,3-dihydro-1H-inden-4-ol → HCID 67238542, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylidene-2,3-dihydro-1H-inden-4-ol | HCID 45082820 | — |
| Reactant | 2-Chloro-oxazole-4-carboxylic acid [1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-amide | HCID 67110887 | — |
| Product | HCID 67238542 | HCID 67238542 | 77% |
Reaction Steps
2-Chloro-oxazole-4-carboxylic acid [1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-amide (50 mg, 0.13 mmol) was reacted with 1-methylene-indan-4-ol (38 mg, 0.26 mmol) prepared as in example 30 to give the title compound (49 mg, 77%) after purification by column chromatography (gradient 12% to 100% EtOAc in n-hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691855B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-2905dc5f92494088b4c7a236ddffe175 |
| Source note | uspto-grants-2014_04 |