HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58319201, compound → HCID 67237446, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58319201 | HCID 58319201 | — |
| Reactant | 2-Chloro-oxazole-4-carboxylic acid [1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-amide | HCID 67110887 | — |
| Product | HCID 67237446 | HCID 67237446 | 81.5% |
Reaction Steps
2-Chloro-oxazole-4-carboxylic acid [1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-amide (50 mg, 0.13 mmol) was reacted with 3-isopropyl-5-trifluoromethyl-phenol (54 mg, 0.26 mmol) to give the title compound (58 mg, 81%) after purification by column chromatography (gradient 12% to 100% EtOAc in n-hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691855B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-04a2d7574f1b452b88aa8d77e64102df |
| Source note | uspto-grants-2014_04 |