HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropylboronic acid → HCID 58319211, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropylboronic acid | HCID 2760897 | — |
| Reactant | HCID 58319305 | HCID 58319305 | — |
| Product | HCID 58319211 | HCID 58319211 | 53.4% |
Reaction Steps
tert-Butyl-(2-cyclopropyl-5-trifluoromethyl-phenoxy)-dimethyl-silane (268 mg, 0.862 mmol) was reacted with cyclopropyl boronic acid (96 mg, 1.12 mmol) as described above to give 2-cyclopropyl-5-trifluoromethyl-phenol (93 mg, 53%) after purification by column chromatography (gradient 12% to 100% EtOAc in n-hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691855B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-6a0bd988b429433eb9ad0622c1f2418d |
| Source note | uspto-grants-2014_04 |