2-Amino-carbethoxycarbonylmethyl-quinoxalinium bromide → Ethyl imidazo[1,2-a]quinoxaline-2-carboxylate

Participants

Reaction Steps

A suspension of 0.4 g of the product of Step A in 15 ml of ethanol was refluxed for 2 hours and the resulting clear orange solution was concentrated to half its volume. The mixture was filtered to obtain 0.25 g of ethyl imidazo-[1,2-a]-quinoxaline-2-carboxylate as a pale yellow solid which were crystallized from an ether-methanol mixture to obtain the product in the form of soft-white needles melting at 184°-187° C. with decomposition.

Provenance & Evidence