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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2363156Generated: October 31, 2026

4-tert-Butylphenylboronic acid → HCID 67237836, compound

https://huagongshe.com/reaction/2363156

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-tert-Butylphenylboronic acidHCID 2734320—
ReactantHCID 67111227HCID 67111227—
ProductHCID 67237836HCID 6723783671%

Reaction Steps

5-Bromo-thiophene-2-carboxylic acid 3,5-difluoro-4-methanesulfonylamino-benzylamide (80 mg, 0.19 mmol) was reacted with 4-tert-butyl phenyl boronic acid (40.2 mg, 0.23 mmol) to give the title compound (64 mg, 71%) after purification by column chromatography (gradient 12% to 100% EtOAc in n-hexane).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08691855B2
Source datasetuspto-grants-2014_04
ORD IDord-f8fd618557c54b46bfe52e49c36f4659
Source noteuspto-grants-2014_04