HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-tert-Butylphenylboronic acid → HCID 67237836, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-tert-Butylphenylboronic acid | HCID 2734320 | — |
| Reactant | HCID 67111227 | HCID 67111227 | — |
| Product | HCID 67237836 | HCID 67237836 | 71% |
Reaction Steps
5-Bromo-thiophene-2-carboxylic acid 3,5-difluoro-4-methanesulfonylamino-benzylamide (80 mg, 0.19 mmol) was reacted with 4-tert-butyl phenyl boronic acid (40.2 mg, 0.23 mmol) to give the title compound (64 mg, 71%) after purification by column chromatography (gradient 12% to 100% EtOAc in n-hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691855B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-f8fd618557c54b46bfe52e49c36f4659 |
| Source note | uspto-grants-2014_04 |