HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Methoxyphenyl)boronic acid → HCID 67111279, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Methoxyphenyl)boronic acid | HCID 2734370 | — |
| Reactant | 2-Chloro-oxazole-4-carboxylic acid [1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-amide | HCID 67110887 | — |
| Product | HCID 67111279 | HCID 67111279 | 12.8% |
Reaction Steps
2-Chloro-oxazole-4-carboxylic acid [1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-amide (100 mg, 0.26 mmol) was reacted with 3-methoxy phenyl boronic acid (48 mg, 0.32 mmol) to give the title compound (15 mg, 10%) after purification by column chromatography (gradient 12% to 100% EtOAc in n-hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691855B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-008bf1b1766149dfa30c3416a4511374 |
| Source note | uspto-grants-2014_04 |