HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-5-(trifluoromethyl)benzaldehyde → 1-Bromo-3-ethenyl-5-(trifluoromethyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-5-(trifluoromethyl)benzaldehyde | HCID 16115438 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Product | 1-Bromo-3-ethenyl-5-(trifluoromethyl)benzene | HCID 67111980 | 79% |
Reaction Steps
3-Bromo-5-trifluoromethylbenzaldehyde (1.10 g, 4.3 mmol) was reacted with CH3PPh3I (2.2 g, 5.4 mmol) and t-BuOK (710 mg, 6.3 mmol) as described above to give 1-bromo-3-trifluoromethyl-5-vinyl-benzene (850 mg, 79%) after purification by flash chromatography on silica gel
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691855B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-d918e7b6f1c14c5f96a9d9fd63e52c89 |
| Source note | uspto-grants-2014_04 |