Cesium carbonate → HCID 44603390, compound

Participants

Reaction Steps

2-(3-Trifluoromethyl-5-vinyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (135 mg, 0.45 mmol) and 5-bromo-furan-2-carboxylic acid [1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-amide (130 mg, 0.31 mmol) was reacted using Pd(PPh3)2Cl2 (20 mg, 0.03 mmol), Cs2CO3 (300 mg, 0.92 mmol) as described above to give the title compound (100 mg, 63%) after purification by flash chromatography on silica gel (hexane: EtOAc=1:1).

Provenance & Evidence