3,5-Dichloro-4-hydroxybenzoic acid → 3-({1-[2-(3,5-Dichloro-4-hydroxybenzoylamino)-3-methanesulfonyl-propionyl]-pyrrolidine-2-carbonyl}-amino)-4-oxo-butyric Acid

Participants

Role	Name	HCID	Charge
Reactant	3,5-Dichloro-4-hydroxybenzoic acid	HCID 18749	—
Reactant	3-({1-[2-(4-Amino-3-chloro-benzoylamino)-3-methylsulfonyl-propionyl]-pyrrolidine-2-carbonyl}-amino)-4-oxo-butyric acid	HCID 18623771	—
Product	3-({1-[2-(3,5-Dichloro-4-hydroxybenzoylamino)-3-methanesulfonyl-propionyl]-pyrrolidine-2-carbonyl}-amino)-4-oxo-butyric Acid	HCID 18623770	—

Reaction Steps

Compound 20s was prepared according to the procedure used for the preparation of 20i, using 3,5-dichloro-4-hydroxybenzoic acid in place of 1-isoquinolinecarboxylic acid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08691848B2
Source dataset	uspto-grants-2014_04
ORD ID	ord-8ace0bd9495343c9bd60b3d8fcfcd27a
Source note	uspto-grants-2014_04