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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 236338Generated: October 29, 2026

Trifluoroacetic acid → HCID 70433992, compound

https://huagongshe.com/reaction/236338

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 18596601HCID 18596601—
ProductHCID 70433992HCID 70433992—

Reaction Steps

The (3S)-2-[(2RS)-3-tert.butoxycarbonylamino-2-methylpropanoyl]-3-carboxy-1,2,3,4-tetrahydroisoquinoline obtained is treated with trifluoroacetic acid according to the method in Example 1 (Step E), providing (3S)-2-[(2RS)-3-amino-2-methylpropanoyl]-3-carboxy-1,2,3,4-tetrahydroisoquinoline trifluoroacetate, which is transformed into the hydrochloride by being dissolved in an excess of normal HCl and concentrated to dryness.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04644008
Source datasetuspto-grants-1987_02
ORD IDord-695f33bc973048769f1d5e2356233b95
Source noteuspto-grants-1987_02