Hydrochloric Acid → HCID 13536822, compound

Participants

Reaction Steps

A mixture of 3.0 g of 7-(1-ethoxycarbonylethyl)oxy-3-(3-hydroxyphenyl)-4H-1-benzopyran-4-one, 90 ml of dioxane, 120 ml of water and 15 ml of hydrochloric acid was refluxed for 2.5 hours, poured into ice water and extracted with ethyl acetate. The extract was washed with water and concentrated and the residue was recrystallized from ethyl acetate-dichloroethane to give 2.5 g of 7-(1-hydroxycarbonylethyl)oxy-3-(3- hydroxyphenyl)-4H-1-benzopyran-4-one as white crystals. m.p. 218°-219° C.

Provenance & Evidence