N-phenyl-6-(pyrid-2-yl)imidazo[1,2-a]pyridine-2-carboxamide → 5-Methyl-N-phenyl-6-(pyrid-2-yl)imidazo[1,2-a]pyridine-2-carboxamide

HRID 2363714Notes

Reaction equation

HRID 2363714 reaction equation
[C:1]1([NH:7][C:8]([C:10]2[N:11]=[C:12]3[CH:17]=[CH:16][C:15]([C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=4)=[CH:14][N:13]3[CH:24]=2)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.I[C:26]1C=CC2N(C(C3C=CC=CN=3)=C(C(NC3C=CC=CC=3)=O)N=2)C=1C>>[CH3:26][C:14]1[N:13]2[CH:24]=[C:10]([C:8]([NH:7][C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[O:9])[N:11]=[C:12]2[CH:17]=[CH:16][C:15]=1[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=1

Participants

3

Reactant 2

HCID 68779277N-phenyl-6-(pyrid-2-yl)imidazo[1,2-a]pyridine-2-carboxamideHCID 68780972HCID 68780972, compound

Product 1

HCID 687805325-Methyl-N-phenyl-6-(pyrid-2-yl)imidazo[1,2-a]pyridine-2-carboxamide

Procedure

This product is obtained in a manner similar to that for the product of Example 3, replacing the 6-iodo-N-phenylimidazo[1,2-a]pyridine-2-carboxamide with 6-iodo-5-methyl-N-phenyl(pyrid-2-yl)imidazo[1,2-a]pyridine-2-carboxamide.

Sources & evidence

ORD record
ord-b92f1c3602e547b6979c5aa4929faa7d
Source dataset
uspto-grants-2014_04
Patent number
US08691990B2

Reaction notes

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