HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 6-Cyanoimidazo[1,2-a]pyridine-2-carboxylate → N-phenyl-6-cyanoimidazo[1,2-a]pyridine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 6-Cyanoimidazo[1,2-a]pyridine-2-carboxylate | HCID 10512851 | — |
| Reactant | 6-bromo-N-phenylimidazo[1,2-a]pyridine-2-carboxamide | HCID 24771673 | — |
| Product | N-phenyl-6-cyanoimidazo[1,2-a]pyridine-2-carboxamide | HCID 44135940 | — |
Reaction Steps
By working in the same manner as for the preparation of Intermediate 1, replacing the ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate with ethyl 6-cyanoimidazo[1,2-a]pyridine-2-carboxylate (J. Med. Chem. (1998), 41(22), 4317), N-phenyl-6-cyanoimidazo[1,2-a]pyridine-2-carboxamide is obtained in the form of a yellow solid
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691990B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-fcce91f6a0394997a21fd452a65e36a7 |
| Source note | uspto-grants-2014_04 |