HRID2363735

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)OC(=O)Nc1cccc(-c2ccc3nc(C(=O)O)cn3c2)n1

HCID44124940

未命名化合物

结构：CCOC(=O)c1cn2cc(-c3csc(NC(=O)OC(C)(C)C)n3)ccc2n1

HCID44136202

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)Nc1nc(-c2ccc3nc(C(=O)O)cn3c2)cs1

HCID44124943

未命名化合物

收率 77.6%

PROCEDURE

实验过程

125 mg of ethyl 6-(2-{[(1,1-dimethylethoxy)carbonyl]amino}thiazol-4-yl)imidazo[1,2-a]pyridine-2-carboxylate are saponified under conditions similar to those described for the preparation of Intermediate 11 (step 11.3), to give 90 mg of 6-(2-{[(1,1-dimethylethoxy)carbonyl]amino}thiazol-4-yl)imidazo[1,2-a]pyridine-2-carboxylic acid in the form of a brown solid.