HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2363738Generated: October 29, 2026
1H-Pyrazole-4-boronic acid → ethyl 6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyridine-2-carboxylate
https://huagongshe.com/reaction/2363738
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1H-Pyrazole-4-boronic acid | HCID 17750278 | — |
| Reactant | Ethyl 6-[1-(triisopropylsilyl)-1H-pyrrol-3-yl]imidazo[1,2-a]pyridine-2-carboxylate | HCID 44136203 | — |
| Product | ethyl 6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyridine-2-carboxylate | HCID 44136205 | — |
Reaction Steps
This product is prepared under conditions similar to those described for the preparation of Intermediate 15 (step 15.1), replacing the 1-(triisopropylsilyl)pyrrole-3-boronic acid with pyrazole-4-boronic acid and heating at 90° C. by microwave for 37 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08691990B2 |
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| Source dataset | uspto-grants-2014_04 |
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| ORD ID | ord-5dabd9eec4e04e33bede1cc194544f7a |
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| Source note | uspto-grants-2014_04 |
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