Hydrogen Peroxide → HCID 14433155, compound

Participants

Reaction Steps

To a solution of anhydrodihydroartemisinin (AHA) (2.08 g, 7.8 mmol) in THF (20 ml), was dropwise added a solution of BH3/THF complex in THF soln. (1 M; 14 ml) with ice-cooling. After being stirred at room temperature for 1 h, the mixture was treated with THF-water (1:1; 4 ml), followed by a mixture of aq. KOH (10%; 10 ml) and aq. H2O2 (50%; 4 ml).

Provenance & Evidence