Ethanolamine → HCID 86762320, compound

Participants

Reaction Steps

This compound was prepared from ethyl 1-[2-(1,1-dioxidotetrahydro-2H-1,2-thiazin-2-yl)ethyl]-7-[(4-fluorophenyl)methyl]-4-hydroxy-2-oxo-1,2-dihydro-1,5-naphthyridine-3-carboxylate and ethanolamine employing methods similar to those described in Example 202 and was obtained as a white solid: 1H NMR (300 MHz, CDCl3) δ 10.40 (s, 1 H), 8.58 (s, 1 H), 7.88 (s, 1 H), 7.24 (m, 2 H), 7.01 (t, J=8.5 Hz, 2 H), 4.40 (m, 2 H), 4.13 (s, 2 H), 3.87 (m, 2 H), 3.66 (m, 2 H), 3.43-3.36 (m, 4 H), 2.97 (m, 2 H), 2.19 (m, 2 H), 1.60 (m, 2 H); MS m/z 519 (M+H)+.

Provenance & Evidence