4-(Methylsulfonyl)benzaldehyde → HCID 69480978, compound

HRID 2364311Notes

Reaction equation

HRID 2364311 reaction equation
[NH2:1][C:2]1[C:3]([C:16]([O:18][CH2:19][CH3:20])=[O:17])=[N:4][CH:5]=[C:6]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([F:15])=[CH:11][CH:10]=2)[CH:7]=1.[CH3:21][S:22]([C:25]1[CH:32]=[CH:31][C:28]([CH:29]=O)=[CH:27][CH:26]=1)(=[O:24])=[O:23]>>[F:15][C:12]1[CH:11]=[CH:10][C:9]([CH2:8][C:6]2[CH:7]=[C:2]([NH:1][CH2:29][C:28]3[CH:27]=[CH:26][C:25]([S:22]([CH3:21])(=[O:24])=[O:23])=[CH:32][CH:31]=3)[C:3]([C:16]([O:18][CH2:19][CH3:20])=[O:17])=[N:4][CH:5]=2)=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 2203764-(Methylsulfonyl)benzaldehydeHCID 42637772Ethyl 3-amino-5-(4-fluorobenzyl)picolinate

Product 1

HCID 69480978HCID 69480978, compound

Procedure

This compound was prepared from ethyl 3-amino-5-[(4-fluorophenyl)methyl]-2-pyridinecarboxylate and 4-methylsulfonyl benzaldehyde employing methods similar to those described in Example 265 and was obtained as a yellow solid.

Workup

  1. customwas obtained as a yellow solid

Sources & evidence

ORD record
ord-3dc97af2af244dfaac2862e5a3a578d5
Source dataset
uspto-grants-2014_04
Patent number
US08691991B2

Reaction notes

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