Ethanolamine → HCID 69480886, compound

Participants

Reaction Steps

This compound was prepared from ethyl 7-[(4-fluorophenyl)methyl]-4-hydroxy-1-{[4-(methylsulfonyl)phenyl]methyl}-2-oxo-1,2-dihydro-1,5-naphthyridine-3-carboxylate and ethanolamine employing methods similar to those described in Example 202 and was obtained as a white solid. 1H NMR (400 MHz, CD3OD) δ 8.53 (s, 1 H), 7.81 (d, J=8.2 Hz, 2 H), 7.19 (d, J=8.1 Hz, 2 H), 7.05 (s, 1 H), 6.98-6.95 (m, 4 H), 5.41 (br, 2 H), 4.00 (s, 2 H), 3.78 (t, J=5.2 Hz, 2 H), 3.60 (m, 2 H), 3.01 (s, 3 H); HRMS C26H24FN3O6S (M+H)+ calcd 526.1370, found 526.1434.

Provenance & Evidence